Katelynn R. Kazane

This study shows that KMT2D promotes effector molecule release in NK cells by regulating H3K4me1 and RAB3D levels, affecting cytotoxicity and cytokine production.

This study identifies fatty acids as regulators of stem-like exhausted CD8 T cells during chronic viral infection, showing their impact on mitochondrial fitness and viral control.

This study identifies LDHB as a key regulator of pDC IFN-I production and metabolic capacity during viral infection, linking metabolic deficiencies to pDC exhaustion and its dual role in immunity and pathology.

The paper identifies CDC7 inhibition as a method to enhance HDR efficiency in CRISPR-Cas9 gene editing by inducing an early S-phase cell cycle arrest.

This paper introduces DISCOVER-Seq, a method to detect CRISPR off-targets in vivo with single-base resolution, applicable to multiple Cas nucleases.

This paper uses HiChIP to map enhancer-promoter interactions in primary human cells, linking disease-associated DNA variants to their target genes.