Author

Nadine A. Hoffmann

University of Tübingen

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

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Alejandra AlvaradoiD· 1 shared Amelie StadelmanniD· 1 shared Elisabeth Lorenz· 1 shared Fabian SmollichiD· 1 shared Hannes LinkiD· 1 shared Jennifer MülleriD· 1 shared Knut DrescheriD· 1 shared Nils Waffenschmidt· 1 shared

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1 shared paperMicrobiology

Alejandra AlvaradoORCID

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1 paper

Recent·Most cited

MicrobiologyMolecular Systems BiologyPeer-reviewedJan 2, 2025

Purine nucleotide limitation undermines antibiotic action in clinical Escherichia coli

Paul Lubrano, Fabian Smollich, Thorben Schramm…·Hannes Link

This study identifies purine nucleotide limitation as a mechanism conferring antibiotic resistance in E. coli by reducing ATP supply and upregulating the purine nucleoside transporter PunC.

19 citationstop 2%

E. coliproteomics

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