Author

Naganori Nao

Hokkaido University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Rigel SuzukiiD· 4 shared Saori SuzukiiD· 4 shared Takasuke FukuharaiD· 4 shared Tomokazu TamuraiD· 4 shared Jingshu LiiD· 3 shared Jumpei ItoiD· 3 shared Kazuo TakayamaiD· 3 shared Kei SatoiD· 3 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

Rigel SuzukiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Involvement of Hepatitis B Core-Related Antigen in Viral Genome Integration in Patients With Prior Hepatitis B Virus Infection

Tomoya Saito, Rigel Suzuki, Akhinur Rahman, Kento Mori, Samiul Alam Rajib, Nobuhiro Kobayashi, Yoichi Yamamoto, Sharmin Nahar Sithi, Takaya Ichikawa, Tatsuya Orimo, Tatsuhiko Kakisaka, Lihan Liang, Naganori Nao, Saori Suzuki, Tomokazu Tamura, , Takasuke Fukuhara

The study investigates HBV genome integration in HBcAb-positive NBNC-HCC patients and finds HBV integration near TERT, KMT2B, and LOC441666, with HBcrAg as a potential marker for HBV detection.

Hepatology Research · Mar 24, 2026Peer-reviewedMicrobiology

A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

Shuhei Tsujino, Masumi Tsuda, Sayaka Deguchi, Jumpei Ito, Taha Y. Taha, Hesham Nasser, Lei Wang, Julia Rosecrans, Rigel Suzuki, Saori Suzuki, Kumiko Yoshimatsu, Mélanie Ott, Terumasa Ikeda, Kei Sato, Kazuo Takayama, , Miki Kawano

This study identifies the non-spike R204P mutation in the SARS-CoV-2 Omicron XEC variant as a driver of increased inflammation and pathogenicity through NF-κB activation.

Nature Communications · Dec 14, 2025Peer-reviewedMicrobiology

A Protein Language Model for Exploring Viral Fitness Landscapes

Jumpei Ito, Adam Patrick Strange, Wei Liu, Gustav Joas, Spyros Lytras, Keita Matsuno, Naganori Nao, Hirofumi Sawa, Keita Mizuma, Isshu Kojima, Jingshu Li, Tomoya Tsubo, Shinya Tanaka, Masumi Tsuda, Lei Wang, , Kei Sato

This paper introduces CoVFit, a protein language model that predicts SARS-CoV-2 variant fitness using spike protein sequences, identifying fitness-enhancing mutations and predicting emerging variants.

Nature Communications · May 13, 2025Peer-reviewedMicrobiology

Evolution of BA.2.86 to JN.1 reveals functional changes in non-structural viral proteins are required for fitness of SARS-CoV-2

Shuhei Tsujino, Masumi Tsuda, Naganori Nao, Kaho Okumura, Lei Wang, Yoshitaka Oda, Yume Mimura, Jingshu Li, Rina Hashimoto, Yasufumi Matsumura, Rigel Suzuki, Saori Suzuki, Kumiko Yoshimatsu, Miki Nagao, Jumpei Ito, , Takasuke Fukuhara

This study investigates the evolutionary changes from BA.2.86 to JN.1, showing that non-spike protein mutations compensate for reduced spike protein replication, enhancing viral fitness.

bioRxiv · Feb 17, 2025 · PreprintMicrobiology