Cyclic azapeptide cluster of differentiation-36 receptor modulator attenuates left ventricular injury and temporarily reduces long-chain fatty acid accumulation after myocardial ischemia-reperfusion in mice
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel
This study shows that the CD36 modulator MPE-298 reduces infarct size and LCFA accumulation in mice after myocardial ischemia-reperfusion.
FEBS Open Bio · May 7, 2026Peer-reviewedPharmacology & Toxicology