Caroline Daneault

This study shows that the CD36 modulator MPE-298 reduces infarct size and LCFA accumulation in mice after myocardial ischemia-reperfusion.

The paper identifies neuronal lipid droplets as conserved structures that regulate energy homeostasis with sex-biased effects in flies and mice.

This study investigates whether inhibiting stearoyl-CoA desaturase (SCD) restores sleep in 3xTg-AD mice and affects astrocytic function, finding no significant restoration of sleep patterns but partial rescue of astrocytic changes in the hippocampus.

This study tracks liver disease progression in PEX1-G844D mice, identifying peroxisomal dysfunction and metabolic changes that contribute to hepatosteatosis, inflammation, fibrosis, and cancer.

This study uses machine learning and explainable AI to identify metabolite markers for heart failure, finding that lignoceric acid is a significant discriminator.

This study shows that inhibiting ATGL in microglia reduces LPS-induced inflammation and sickness behavior in mice.