Matthieu Ruiz

This study shows that the CD36 modulator MPE-298 reduces infarct size and LCFA accumulation in mice after myocardial ischemia-reperfusion.

The paper identifies neuronal lipid droplets as conserved structures that regulate energy homeostasis with sex-biased effects in flies and mice.

This study tracks liver disease progression in PEX1-G844D mice, identifying peroxisomal dysfunction and metabolic changes that contribute to hepatosteatosis, inflammation, fibrosis, and cancer.

This study shows that a B vitamin cocktail improves cardiac function and mitochondrial health in a mouse heart failure model, with sex-specific effects.

This study uses machine learning and explainable AI to identify metabolite markers for heart failure, finding that lignoceric acid is a significant discriminator.

This study shows that inhibiting ATGL in microglia reduces LPS-induced inflammation and sickness behavior in mice.

This paper introduces the shortest reactional distance (SRD) metric to improve the biological interpretation of metabolite genome-wide association study (mGWAS) results by linking genes to metabolites based on metabolic pathway knowledge.