Mutations in the Drosophila splicing regulator Prp31 as a model for Retinitis pigmentosa 11
Malte Lehmann, Sarita Hebbar, Holger Brandl, Weihua Leng, Naharajan Lakshmanaperumal, Sylke Winkler, Elisabeth Knust
This study uses a Drosophila model to investigate the effects of Prp31 mutations, showing light-induced retinal degeneration linked to oxidative stress and splicing defects.
bioRxiv · Jun 9, 2017 · PreprintGenetics