Author

Elisabeth Knust

Max Planck Institute of Molecular Cell Biology and GeneticsORCID 0000-0002-2732-9135Unclaimed ORCID profile · follow to get notified of new preprints

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Elisabeth Knust1 paper

Biology Disciplines

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Genetics· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Sarita HebbariD· 3 shared Malte LehmanniD· 2 shared Sylke WinkleriD· 2 shared Weihua Leng· 2 shared B. Grygo Sarah· 1 shared Catrin Hälsig· 1 shared Christos SamakovlisiD· 1 shared Dilan KhaliliiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

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10 top collaborators · 18 mutual co-author links

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3 shared papersGenetics

Sarita HebbarORCID

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4 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 10, 2022

Modulating the Kynurenine pathway or sequestering toxic 3-hydroxykynurenine protects the retina from light induced damage in Drosophila

Sarita Hebbar, Sofia Traikov, Catrin Hälsig, Elisabeth Knust

DOI 10.1101/2022.09.10.507411

Drosophilaexperimental assay

Developmental BiologyThe Journal of Cell BiologyPeer-reviewedJul 17, 2019

Yorkie controls tube length and apical barrier integrity in the developing Drosophila airways

Kassiani Skouloudaki, Ioannis Christodoulou, Dilan Khalili…·Dimitrios K. Papadopoulos

This paper identifies Yorkie's dual role in regulating tracheal tube length and apical barrier integrity in Drosophila airways through cytoplasmic and transcriptional mechanisms.

17 citations

Drosophilastatistical model

GeneticsbioRxivPreprintAug 13, 2018

The splicing regulator Prp31 prevents retinal degeneration in Drosophila by regulating Rhodopsin levels

Malte Lehmann, Sarita Hebbar, B. Grygo Sarah…·Elisabeth Knust

This study shows that mutations in the splicing factor Prp31 in Drosophila cause light-dependent retinal degeneration by increasing rhodopsin 1 accumulation, which can be mitigated by reducing rhodopsin levels.

DOI 10.1101/386433

Drosophilaexperimental assay

GeneticsbioRxivPreprintJun 9, 2017

Mutations in the Drosophila splicing regulator Prp31 as a model for Retinitis pigmentosa 11

Malte Lehmann, Sarita Hebbar, Holger Brandl…·Elisabeth Knust

This study uses a Drosophila model to investigate the effects of Prp31 mutations, showing light-induced retinal degeneration linked to oxidative stress and splicing defects.

DOI 10.1101/147918

Drosophilabulk RNA-seq