Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements
Byungjin Hwang, Wookjae Lee, Soo‐Young Yum, Yujin Jeon, Namjin Cho, Goo Jang, Duhee Bang
This paper develops a genetic barcode system using a Cas9-deaminase to trace cell lineage in mammals, showing accurate reconstruction of lineage from bulk and single-cell data.
Nature Communications · Mar 15, 2019Peer-reviewedGenomics