B cell receptor dependent enhancement of dengue virus infection
Chad Gebo, C. S. C. Hardy, Benjamin D. McElvany, Nancy R. Graham, Joseph Q. Lu, Shima Moradpour, Jeffrey R. Currier, Heather Friberg, Gregory D. Gromowski, Stephen James Thomas, Gary C. T. Chan, Sean A. Diehl, Adam Tully Waickman
This study shows that DENV infection enhances B cells via their BCR, linking ADE potential to B cell susceptibility and highlighting B cells as a key reservoir in immune-mediated DENV enhancement.
PLoS Pathogens · Oct 31, 2024Peer-reviewedImmunology