This study compares the immunotranscriptomic features of DENV-1, -3, and -4 human challenge models to identify gene expression patterns associated with RNAemia and clinical symptoms.

The Journal of Infectious Diseases · Jun 25, 2026Peer-reviewedImmunology

Antibody response to Aedes aegypti D7L1+2 salivary proteins as marker of aggregate vector exposure and correlate of dengue virus susceptibility

Lauren E. Bahr, Marco Hamins-Puértolas, Darunee Buddhari, Ivona Petzlova, Fabiano Oliveira, Stephen James Thomas, Saravanan Thangamani, Adam Tully Waickman, Kathryn B. Anderson

The paper develops a serologic assay to measure antibodies against Aedes aegypti salivary proteins D7L1+2 as a marker of vector exposure and finds they correlate with dengue virus infection burden.

PLoS neglected tropical diseases · Oct 29, 2025Peer-reviewedImmunology

B cell receptor dependent enhancement of dengue virus infection

Chad Gebo, C. S. C. Hardy, Benjamin D. McElvany, Nancy R. Graham, Joseph Q. Lu, Shima Moradpour, Jeffrey R. Currier, Heather Friberg, Gregory D. Gromowski, Stephen James Thomas, Gary C. T. Chan, Sean A. Diehl, Adam Tully Waickman

This study shows that DENV infection enhances B cells via their BCR, linking ADE potential to B cell susceptibility and highlighting B cells as a key reservoir in immune-mediated DENV enhancement.

PLoS Pathogens · Oct 31, 2024Peer-reviewedImmunology