The stress response factor SigH mediates intrinsic resistance to multiple antibiotics in Mycobacterium abscessus
Md Shah Alam, Mst Sumaia Khatun, Buhari Yusuf, Li Li, Belachew Aweke Mulu, Haftay Abraha Tadesse, Junhua Zhang, Xirong Tian, Cuiting Fang, Gao Y, Z.H. Liu, Jinxing Hu, Xinwen Chen, Nanshan Zhong, Liqiang Feng, , Tianyu Zhang
This study identifies SigH as a key regulator of intrinsic antibiotic resistance in Mycobacterium abscessus through transcriptomic analysis and genetic complementation.
Microbiology Spectrum · Jun 15, 2026Peer-reviewedMolecular Biology