Junhua Zhang

The stress response factor SigH mediates intrinsic resistance to multiple antibiotics in Mycobacterium abscessus

This study identifies SigH as a key regulator of intrinsic antibiotic resistance in Mycobacterium abscessus through transcriptomic analysis and genetic complementation.

DigiMus: a connectome-informed spiking framework for multi-region mouse neural-behavior modeling

DigiMus integrates connectome-derived structural priors into a spiking neural network framework for mouse neural-behavior modeling, showing improved performance in complex tasks.

PhosSight: a Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

PhosSight improves phosphoproteome identification by addressing acquisition biases in DDA and DIA, enhancing sensitivity and reducing missing values in cancer research.

Causally validated phase-amplitude coupling enables high-fidelity motor decoding for next-generation brain-computer interfaces

This paper shows that phase-amplitude coupling (PAC) improves motor decoding in BCIs compared to traditional methods by using Beta-PAC as a more accurate feature.

Pan-cancer transcriptional regulatory network analysis reveals key drivers and epigenetic modulators in tumorigenesis

The paper constructs pan-cancer transcriptional regulatory networks using multi-omics data, identifying key transcription factors and epigenetic modulators involved in tumorigenesis.