Computational Prediction of Synthetic Circuit Function Across Growth Conditions
Bree Cummins, Robert C. Moseley, Anastasia Deckard, Mark Weston, George Zheng, Daniel Bryce, Joshua Nowak, Marcio Gameiro, Tomáš Gedeon, Konstantin Mischaikow, Jacob Beal, Tessa Johnson, Matthew W. Vaughn, Niall I. Gaffney, Shweta Gopaulakrishnan, , Steven B. Haase
The paper develops a computational method to predict synthetic circuit robustness across growth conditions and validates it with experimental results in budding yeast.
bioRxiv · Jun 13, 2022 · PreprintSynthetic Biology