PfApiAT2 is a proline transporter essential for the transmission of Plasmodium falciparum by the mosquito vector.
Malhar Khushu, R. Charles Kissell, Jamie Kauffman, Claudia Taccheri, Naresh Singh, Robert L. Summers, Leigh Daniel Plant, Dyann F. Wirth, Flaminia Catteruccia, Selina E. R. Bopp
The paper identifies PfApiAT2 as a proline transporter essential for Plasmodium falciparum oocyst development in mosquitoes, showing that its absence leads to defective sporozoite production and oocyst degeneration.
Nature Communications · Jul 3, 2026Peer-reviewedMicrobiology