Kenshiro Fujise

This study identifies synaptogyrin family proteins as key regulators of dopamine vesicle formation, overriding canonical synaptic vesicle size constraints and contributing to dopaminergic terminal vulnerability in Parkinson's disease.

The paper identifies BLTP3A as a protein associated with late endocytic membranes and shows it interacts with the CASM pathway to respond to lysosome damage.

This study identifies interactions that mediate BLTP2 localization at ER-PM contacts and shows its role in controlling plasma membrane dynamics through lipid transport.

The paper characterizes synaptic vesicles in iPSC-derived dopaminergic neurons, revealing distinct secretory vesicle pools with different molecular and ultrastructural features.

The paper shows that synaptophysin and synaptogyrin family proteins co-express with synapsin to generate small vesicles and that their absence leads to larger synaptic vesicles.

This study investigates how a mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons, revealing impaired protein clearance and altered Ca2+ channel distribution.