Deciphering Brain Organoids Heterogeneity by Identifying Key Quality Determinants
Daniel V. Kachkin, Naime Zagha, Tom Boerstler, Federica Furlanetto, Negar Nayebzade, Luke Zappia, Michelle Boisvert, Michaela Farrell, Sonja Ploetz, Martin Regensburger, Claudia Günther, Jürgen Winkler, Pooja Gupta, Fabian Joachim Theis, Marisa Karow, , Florian Krach
The paper identifies the Feret diameter as a reliable quality marker for brain organoids and shows mesenchymal cells negatively impact organoid formation.
bioRxiv · Jan 13, 2025 · PreprintNeuroscience