Pooja Gupta

This study shows TNF-α disrupts the malate-aspartate shuttle in iPSC-derived enteric neural cells from PD patients, causing metabolic shifts and mitochondrial dysfunction, which can be reversed by targeting glutamate metabolism.

The paper compares 13 mouse models of intestinal inflammation with human IBD datasets to identify translatable pathways and introduces a web tool for analyzing these models.

Dedifferentiated fibroblasts sequentially induce and resolve neutrophil-driven inflammation through cytokine release to facilitate axon regeneration after spinal cord injury in zebrafish.

The paper identifies the Feret diameter as a reliable quality marker for brain organoids and shows mesenchymal cells negatively impact organoid formation.