The paper examines how motor unit recruitment and firing rates change with different hand tasks, showing task-dependent variations in neural drive distribution.

bioRxiv · Sep 9, 2026 · PreprintNeuroscience

Human blood vessel organoids recapitulate key mechanisms of transition from vasculopathy to fibrosis in systemic sclerosis

YanHua Xiao, Xuezhi Hong, Langxian Zhi, Yi-Nan Li, Martin Regensburger, Franz Marxreiter, Boris Görg, Sarah Koziel, Andrea‐Hermina Györfi, Tim Filla, Peter‐Martin Bruch, Philipp Tripal, James Adjaye, Sascha Dietrich, Jürgen Winkler, , Alexandru-Emil Matei

This study uses blood vessel organoids to model systemic sclerosis vasculopathy and fibrosis, showing that SSc serum induces epigenetic and molecular changes linked to endothelial dysfunction and potential therapeutic targets.

Annals of the Rheumatic Diseases · Mar 22, 2026Peer-reviewedBiophysics

Deciphering Brain Organoids Heterogeneity by Identifying Key Quality Determinants

Daniel V. Kachkin, Naime Zagha, Tom Boerstler, Federica Furlanetto, Negar Nayebzade, Luke Zappia, Michelle Boisvert, Michaela Farrell, Sonja Ploetz, Martin Regensburger, Claudia Günther, Jürgen Winkler, Pooja Gupta, Fabian Joachim Theis, Marisa Karow, , Florian Krach

The paper identifies the Feret diameter as a reliable quality marker for brain organoids and shows mesenchymal cells negatively impact organoid formation.

bioRxiv · Jan 13, 2025 · PreprintNeuroscience

Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

Bernt Popp, Mandy Krumbiegel, Janina Grosch, Annika Sommer, Steffen Uebe, Zacharias Kohl, Sonja Plötz, Michaela Farrell, Udo Trautmann, Cornelia S. Kraus, Arif Bülent Ekici, Reza Asadollahi, Martin Regensburger, Katharina Günther, Anita M. Rauch, , André Reis

The paper analyzes genetic integrity in iPSCs from the ForIPS consortium, identifying somatic variants and highlighting the need for individual clone evaluation.

Scientific Reports · Nov 15, 2018Peer-reviewedGenomics