Experience-independent transformation of single-cell 3D genome structure and transcriptome during postnatal development of the mammalian brain
Longzhi Tan, Wenping Ma, Honggui Wu, Yinghui Zheng, Dong Xing, Ritchie Chen, Xiang Li, Nicholas Daley, Karl A. Deisseroth, Xiaoliang Sunney Xie
The paper generates transcriptome and 3D genome atlases of developing mouse brain cells, revealing structure-type-based cell identity and experience-independent developmental changes.
Cell · Jan 22, 2021Peer-reviewedNeuroscience