A programmable probiotic encapsulation system enhances therapeutic delivery in vivo
Tetsuhiro Harimoto, Jaeseung Hahn, Yuyu Chen, Jongwon Im, Joanna T. Zhang, Nicholas Y. Hou, Fangda Li, Courtney Coker, Kelsey Gray, Nicole Harr, Sreyan Chowdhury, Kelly Pu, Clare A. Nimura, Nicholas Arpaia, Kam W. Leong, Tal Danino
This paper develops a programmable probiotic encapsulation system using synthetic biology to enhance therapeutic delivery in mice by controlling bacterial immunogenicity and survivability.
bioRxiv · Aug 3, 2021 · PreprintSynthetic Biology