Joanna T. Zhang

This study shows FAK inhibition in ovarian tumors increases macrophage CXCL13 production via omega-3 fatty acids, enhancing B cell infiltration and immunotherapy response.

This study improves genetic circuit function in E. coli by evolving strains in complex environments using adaptive laboratory evolution.

This paper introduces RGN2, a deep learning model that predicts protein structure from single sequences without MSAs, outperforming AlphaFold2 and RoseTTAFold on orphan proteins and achieving faster computation.

This paper develops a programmable probiotic encapsulation system using synthetic biology to enhance therapeutic delivery in mice by controlling bacterial immunogenicity and survivability.

The paper presents a 3-D multicellular model to rapidly screen engineered microbial therapies, identifying effective antitumor candidates and demonstrating scalability across microbial species.