Maternal antiviral history synergizes with pregnancy and lactation to transfer intergenerational systemic immunity through IgG in milk
Ka Neng Cheong, Juan Sebastián Jara, Leigh M. Sewall, Stanislav Dikiy, Xuan Le, Nicole Wolman, Andrew B. Ward, R. Luke Wiseman, Alejandra Mendoza
This paper shows that maternal antiviral history before pregnancy enhances offspring immunity through IgG in milk, which is transferred via FcRn and provides protection beyond weaning.
bioRxiv · Aug 19, 2026 · PreprintImmunology