Author

Xuan Le

Rice University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alejandra MendozaiD· 1 shared Andrew B. WardiD· 1 shared Andrew R. GilmouriD· 1 shared David RossiD· 1 shared Devon L. KulhanekiD· 1 shared Juan Sebastián JaraiD· 1 shared Ka Neng CheongiD· 1 shared Leigh M. SewalliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Alejandra MendozaORCID

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2 papers

Recent·Most cited

Maternal antiviral history synergizes with pregnancy and lactation to transfer intergenerational systemic immunity through IgG in milk

Ka Neng Cheong, Juan Sebastián Jara, Leigh M. Sewall, Stanislav Dikiy, Xuan Le, Nicole Wolman, Andrew B. Ward, R. Luke Wiseman, Alejandra Mendoza

This paper shows that maternal antiviral history before pregnancy enhances offspring immunity through IgG in milk, which is transferred via FcRn and provides protection beyond weaning.

bioRxiv · Aug 19, 2026 · PreprintImmunology

Mapping the phenotypic landscape of a transcriptional repressor using Deep Mutational Scanning and Growth-based Quantitative Sequencing

Zachary Jansen, Xuan Le, Qiyao Wei, Devon L. Kulhanek, Nina Alperovich, Olga B Vasilyeva, Andrew R. Gilmour, David Ross, Ross T Thyer

The paper uses Deep Mutational Scanning and Growth-based Quantitative Sequencing to analyze CymR variants and identify amino acids essential for repressor function and mutations that improve ligand sensitivity.

Nucleic Acids Research · Feb 24, 2026Peer-reviewedSynthetic Biology