Alejandra Mendoza

This study shows that AA147, a metabolically activated proteostasis regulator, reduces TH17 cell differentiation by degrading RORgammat and IRF4, and dampens effector cytokine responses across T cell subsets.

This paper shows that maternal antiviral history before pregnancy enhances offspring immunity through IgG in milk, which is transferred via FcRn and provides protection beyond weaning.

This study identifies T-bet expressing B cells as critical for mucosal immunity and protection against norovirus infection through IgG and IgA responses.

This study shows that regulatory T cells modulate peripheral neuron activation to restrain skin inflammation by expressing Penk, a precursor for endogenous opioids.