Howard C. Hang

This study shows that NOD2 inhibits TLR2-dependent antitumor immunity induced by Lactiplantibacillus plantarum, highlighting its role as a checkpoint in microbial sensing.

This study shows that inhibiting SagA, a peptidoglycan hydrolase, increases vancomycin susceptibility in VREfm through both genetic and pharmacological approaches.

This study identifies T-bet expressing B cells as critical for mucosal immunity and protection against norovirus infection through IgG and IgA responses.

This study examines allele-specific effects of Rifampin Resistance-Determining Region (RRDR) mutations in RpoB on E. faecium physiology and antibiotic resistance, revealing varied impacts on growth, susceptibility, and hospital survival.

This study identifies sagA mutations in E. faecium that cause cell envelope defects, increasing antibiotic susceptibility and phage sensitivity.

This study identifies DCA as a microbiota-derived bile acid that activates STING and enhances antitumor immunity via NK cell activation.