Author

Niklas Schultz

Karolinska University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Joakim LundebergiD· 3 shared Linda KvastadiD· 3 shared Ludvig LarssoniD· 3 shared Reza MirzazadehiD· 3 shared Alia ShamikhiD· 2 shared Alma AnderssoniD· 2 shared Alastair D.G. LambiD· 1 shared Aleksandra Jurek· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersGenomics

Joakim LundebergORCID

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3 papers

Recent·Most cited

Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples

Reza Mirzazadeh, Žaneta Andrusivová, Ludvig Larsson, Phillip T. Newton, Leire Alonso Galicia, Xesús Manoel Abalo, Mahtab Avijgan, Linda Kvastad, Alexandre Denadai‐Souza, Nathalie Stakenborg, Alexandra B. Firsova, Alia Shamikh, Aleksandra Jurek, Niklas Schultz, Monica Nistér, , Joakim Lundeberg

The paper introduces RRST, a spatial transcriptomics workflow that improves mRNA recovery from low-quality fresh frozen samples, demonstrating its effectiveness across multiple tissue types.

Nature Communications · Jan 31, 2023Peer-reviewedGenomics

Genome-wide Spatial Expression Profiling in FFPE Tissues

Eva Gracia Villacampa, Ludvig Larsson, Reza Mirzazadeh, Linda Kvastad, Alma Andersson, Annelie Mollbrink, Georgia Kokaraki, Vanessa Monteil, Niklas Schultz, K. Sofia Appelberg, Núria Montserrat, Haibo Zhang, Josef Martin Penninger, Wolfgang Miesbach, Alì Mirazimi, , Joakim Lundeberg

This paper presents a method for genome-wide spatial mRNA analysis in FFPE tissues, demonstrating its ability to delineate anatomical regions and analyze transcriptomic signatures in ovarian carcinosarcoma.

Cell Genomics · Dec 1, 2021Peer-reviewedGenetics

The spatial landscape of clonal somatic mutations in benign and malignant tissue

Andrew M. Erickson, Emelie Berglund, Mengxiao He, Maja Marklund, Reza Mirzazadeh, Niklas Schultz, Ludvig Bergenstråhle, Linda Kvastad, Alma Andersson, Joseph Bergenstråhle, Ludvig Larsson, Alia Shamikh, Elisa Basmaci, Teresita Díaz de Ståhl, Timothy Rajakumar, , Joakim Lundeberg

The paper uses spatial transcriptomics to analyze copy number variations in benign and malignant tissues, revealing clonal patterns and suggesting early cancer evolution mechanisms.

bioRxiv · Jul 12, 2021 · PreprintGenomics