Xesús Manoel Abalo

The germline-restricted chromosome orchestrates germ cell development in passerine birds

The paper uses RNA-seq and spatial transcriptomics in zebra finches to study the role of the germline-restricted chromosome (GRC) in germ cell development, identifying its involvement in oocyte maturation and gene expression regulation.

Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples

The paper introduces RRST, a spatial transcriptomics workflow that improves mRNA recovery from low-quality fresh frozen samples, demonstrating its effectiveness across multiple tissue types.

Developmental origins of cell heterogeneity in the human lung

The paper creates a comprehensive topographic atlas of early human lung development, identifying cell states, trajectories, and interactions to understand cell heterogeneity origins.

Super-resolved spatial transcriptomics by deep data fusion

This paper introduces a method to combine histology and spatial gene expression data to infer high-resolution transcriptome maps without sequencing or hybridization.