Author

Noelle Burgess

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bo Am SeoiD· 1 shared Donghoon KimiD· 1 shared Han Seok KoiD· 1 shared Han-Byeol KimiD· 1 shared Javier Redding‐OchoaiD· 1 shared Juan Carlos TroncosoiD· 1 shared Kundlik GadhaveiD· 1 shared Liana S. RosenthaliD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Bo Am SeoORCID

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1 paper

Recent·Most cited

Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease

Bo Am Seo, Seung‐Hwan Kwon, Donghoon Kim, Han-Byeol Kim, Shixun Ma, Kundlik Gadhave, Noelle Burgess, Xiaobo Mao, Liana S. Rosenthal, Javier Redding‐Ochoa, Juan Carlos Troncoso, Seulki Lee, Valina Lynn Dawson, Ted M. Dawson, Han Seok Ko

This paper identifies NOD2/RIPK2 signaling as a key driver of neuroinflammation in Parkinson's disease, showing that pathological α-synuclein activates this pathway in microglia, leading to neurodegeneration and that targeting NOD2 or RIPK2 protects dopamine neurons.

bioRxiv · Feb 19, 2024 · PreprintNeuroscience