Author

Donghoon Kim

Johns Hopkins UniversityORCID 0000-0002-7493-0935Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Han Seok KoiD· 3 shared Ted M. DawsoniD· 3 shared Valina Lynn DawsoniD· 3 shared Bo Am SeoiD· 2 shared Sangjune KimiD· 2 shared Saurav BrahmachariiD· 2 shared Seung‐Hwan KwoniD· 2 shared Xiaobo MaoiD· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Han Seok KoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 19, 2024

Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease

Bo Am Seo, Seung‐Hwan Kwon, Donghoon Kim…·Han Seok Ko

This paper identifies NOD2/RIPK2 signaling as a key driver of neuroinflammation in Parkinson's disease, showing that pathological α-synuclein activates this pathway in microglia, leading to neurodegeneration and that targeting NOD2 or RIPK2 protects dopamine neurons.

3 citations

humanmouse

𝕏 PostBluesky

NeuroscienceJournal of Proteome ResearchPeer-reviewedJun 1, 2021

Complement and coagulation cascades are potentially involved in dopaminergic neurodegeneration in alpha-synuclein-based mouse models of Parkinson's disease

Shi-Xun Ma, Bo Am Seo, Donghoon Kim…·Han Seok Ko

The paper identifies complement and coagulation cascade pathways as significantly altered in two Parkinson's disease mouse models through proteome analysis.

59 citationstop 4%

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 1, 2021

Aplp1 and the Aplp1-Lag3 Complex facilitates transmission of pathologic alpha-synuclein

Xiaobo Mao, Hao Gu, Donghoon Kim…·Ted M. Dawson

The paper identifies Aplp1 and its complex with Lag3 as facilitators of pathologic alpha-synuclein transmission and toxicity, showing that disrupting this complex prevents neurodegeneration.

15 citations

mouseexperimental assay

𝕏 PostBluesky