Author

Seulki Lee

ORCID 0000-0001-7082-154XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Anna D. LouieiD· 1 shared Bo Am SeoiD· 1 shared Donghoon KimiD· 1 shared Han Seok KoiD· 1 shared Han-Byeol KimiD· 1 shared Jared Mompoint· 1 shared Javier Redding‐OchoaiD· 1 shared Juan Carlos TroncosoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Anna D. LouieORCID

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2 papers

Recent·Most cited

Cancer BiologyAmerican Journal of Cancer ResearchPeer-reviewedJan 1, 2025

TRAIL receptor agonist TLY012 in combination with PD-1 inhibition promotes tumor regression in an immune-competent mouse model of pancreatic ductal adenocarcinoma

Anna D. Louie, Kelsey E. Huntington, Young Shin Lee…·Wafik S. El‐Deiry

This study shows that combining TLY012 with PD-1 inhibition reduces PDAC tumor growth in mice by enhancing proinflammatory cytokines and immune cell infiltration.

3 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 19, 2024

Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease

Bo Am Seo, Seung‐Hwan Kwon, Donghoon Kim…·Han Seok Ko

This paper identifies NOD2/RIPK2 signaling as a key driver of neuroinflammation in Parkinson's disease, showing that pathological α-synuclein activates this pathway in microglia, leading to neurodegeneration and that targeting NOD2 or RIPK2 protects dopamine neurons.

3 citations

𝕏 PostBluesky