ImmunologybioRxiv
Charge-Altering Releasable Transporters enable specific phenotypic manipulation of resting primary natural killer cells
A. J. Wilk, N. L. Benner, R. Vergara…·C. A. Blish
This study introduces CARTs, a non-viral transfection method for primary human NK cells, enabling efficient mRNA delivery without activation, preserving phenotype and function, and demonstrating therapeutic potential.
DOI 10.1182/bloodadvances.2020002355