HREM, RNAseq and cell-cycle analyses reveal the role of the G2/M-regulatory protein, Wee1, on the survivability of chicken embryos during diapause.
N. Pokhrel, O. Genin, D. Sela-Donenfeld, Y. Cinnamon
This study uses HREM, RNAseq, and molecular assays to show that Wee1 upregulation during cold diapause arrests the cell cycle, preserving embryonic structure and enabling resumption of development.
bioRxiv · Feb 23, 2022Evolutionary Biology