Glycogen-fuelled metabolism supports rapid Mucosal Associated Invariant T cell responses
F. C. Cassidy, N. Kedia-Mehta, R. Bergin, A. Woodcock, A. Berisha, B. M. Bradley, E. Booth, O. K. Ryan, L. V. Sinclair, D. O'Shea, A. E. Hogan
This study shows glycogen metabolism supports rapid MAIT cell cytotoxicity and cytokine production, which may enhance their use in immunotherapy.
bioRxiv · Dec 20, 2022Immunology