A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoes
C. H. Coelho, W. K. Tang, M. Burkhardt, J. D. Galson, O. Muratova, N. Salinas, T. L. Alves e Silva, K. Reiter, N. MacDonald, V. Nguyen, M. Byrne-Steele, W. Pan, X. Hou, B. Brown, M. Eisenhower, , P. Duffy
The paper identifies a high-affinity human monoclonal antibody against Pfs230 that blocks oocyst formation in mosquitoes by targeting gamete surfaces.
bioRxiv · Sep 25, 2020 · PreprintImmunology