Author

O. N. Witte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. K. Lee· 2 shared A. Petersen· 1 shared A. V. Sheahan· 1 shared C. Morrissey· 1 shared C.-C. Chen· 1 shared D. Cheng· 1 shared D. Shackelford· 1 shared E. Corey· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

J. K. Lee

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2 papers

Recent·Most cited

PGC-1a drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity

G. Varuzhanyan, C.-C. Chen, J. Freeland, T. He, W. Tran, K. Song, L. Wang, D. Cheng, S. Xu, G. A. Dibernardo, F. N. Esedebe, V. Bhatia, M. Han, E. R. Abt, J. W. Park, , O. N. Witte

bioRxiv · Apr 9, 2024Cancer Biology

Targeting RET Kinase in Neuroendocrine Prostate Cancer

H. VanDeusen, J. R. Ramroop, K. L. Morel, A. V. Sheahan, Z. Sychev, N. A. Lau, L. C. Cheng, V. Tan, Z. Li, A. Petersen, J. K. Lee, J. Wook Park, R. Yang, I. Coleman, O. N. Witte, , J. M. Drake

The paper identifies RET kinase as a targetable driver in neuroendocrine prostate cancer (NEPC) through phosphoproteomics and pharmacological inhibition studies, showing reduced tumor growth in models.

bioRxiv · Apr 29, 2019Cancer Biology