Author

O. Waisbourd-Zinman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

R. G. Wells· 3 shared A. Har-Zahav· 2 shared J. Llewellyn· 2 shared Y. Du· 2 shared A. Kriegermeier· 1 shared A. Naji· 1 shared C. J. Soroka· 1 shared C. Liu· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersPhysiology

R. G. Wells

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Author profile →

3 papers

Recent·Most cited

Human Vascularized Bile Duct-on-a Chip: A multi-cellular micro-physiological system for studying Primary Sclerosing Cholangitis

Y. Du, K. Gupta, O. Waisbourd-Zinman, A. Har-Zahav, C. J. Soroka, J. L. Boyer, J. Llewellyn, C. Liu, A. Naji, W. J. Polacheck, R. G. Wells

This paper develops a vascularized bile duct-on-a-chip model to study PSC, showing PSC cholangiocytes exhibit increased inflammation under IL-17A stimulation.

bioRxiv · Mar 2, 2023 · PreprintBioengineering

Periductal bile acid exposure causes cholangiocyte injury and fibrosis

M. Dotan, S. Fried, A. Har-Zahav, R. Shamir, R. G. Wells, O. Waisbourd-Zinman

This study shows that bile acid exposure causes cholangiocyte injury and fibrosis, with a non-toxic bile acid reducing these effects.

bioRxiv · Feb 16, 2022Physiology

Coordinated development of the mouse extrahepatic bile duct: implications for neonatal susceptibility to biliary injury

G. Khandekar, J. Llewellyn, A. Kriegermeier, O. Waisbourd-Zinman, N. Johnson, Y. Du, R. Giwa, X. Liu, T. Kisseleva, P. A. Russo, N. D. Theise, R. G. Wells

This study identifies four key anatomical and functional differences between neonatal and adult mouse extrahepatic bile ducts that may explain their susceptibility to injury.

bioRxiv · Mar 13, 2019Physiology