Author

Oleg Dobrokhotov

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:yeast· 1

Frequent Co-Authors

Chris A. BrackleyiD· 1 shared Frank UhlmanniD· 1 shared Georgii E. PobegaloviD· 1 shared Maxim I. MolodtsoviD· 1 shared Runze Sha· 1 shared Torahiko L. Higashi· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Chris A. BrackleyORCID

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1 paper

Recent·Most cited

Symmetry and force response of cohesin loop extrusion are determined by diffusion of its motor and anchor domains

Maxim I. Molodtsov, Georgii E. Pobegalov, Runze Sha, Oleg Dobrokhotov, Torahiko L. Higashi, Frank Uhlmann, Chris A. Brackley

This study shows cohesin extrudes DNA loops symmetrically or asymmetrically based on applied force, with loop extrusion controlled by stochastic switching of the motor domain and diffusive motion of the anchor domain.

bioRxiv · Jun 10, 2026 · PreprintBiophysics