Author

Omar Ashraf Harb

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Ariadna RobledoiD· 1 shared Carlos Perfecto Flores Suarez· 1 shared Emily K. Alley· 1 shared Gabrielle E. LargozaiD· 1 shared Ionela IacobasiD· 1 shared Jason E. FishiD· 1 shared John J. Ahn· 1 shared Joshua D. WytheiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Ariadna RobledoORCID

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1 paper

Recent·Most cited

MEK signaling represents a viable therapeutic vulnerability of KRAS-driven somatic brain arteriovenous malformations

Carlos Perfecto Flores Suarez, Omar Ashraf Harb, Ariadna Robledo, Gabrielle E. Largoza, John J. Ahn, Emily K. Alley, Ting Wu, Surabi Veeraragavan, Samuel T. McClugage, Ionela Iacobas, Jason E. Fish, Peter Tze Man Kan, Sean P. Marrelli, Joshua D. Wythe

This study shows that KRAS mutations drive brain arteriovenous malformations (bAVMs) in specific brain regions and that MEK inhibition can reduce their severity in mice, suggesting a potential therapeutic approach for human bAVMs.

bioRxiv · May 15, 2024 · PreprintMolecular Biology