Author

Ionela Iacobas

Baylor College of MedicineORCID 0000-0002-9259-8761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Ariadna RobledoiD· 1 shared Carlos Perfecto Flores Suarez· 1 shared Emily K. Alley· 1 shared Gabrielle E. LargozaiD· 1 shared Jason E. FishiD· 1 shared John J. Ahn· 1 shared Joshua D. WytheiD· 1 shared Omar Ashraf Harb· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Ariadna RobledoORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

MEK signaling represents a viable therapeutic vulnerability of KRAS-driven somatic brain arteriovenous malformations

Carlos Perfecto Flores Suarez, Omar Ashraf Harb, Ariadna Robledo, Gabrielle E. Largoza, John J. Ahn, Emily K. Alley, Ting Wu, Surabi Veeraragavan, Samuel T. McClugage, Ionela Iacobas, Jason E. Fish, Peter Tze Man Kan, Sean P. Marrelli, Joshua D. Wythe

This study shows that KRAS mutations drive brain arteriovenous malformations (bAVMs) in specific brain regions and that MEK inhibition can reduce their severity in mice, suggesting a potential therapeutic approach for human bAVMs.

bioRxiv · May 15, 2024 · PreprintMolecular Biology