A membrane homeostatic response to lipid overload coordinates fatty acid metabolism
Xiaojun Xiang, Yohannes Abere Ambaw, Ozlem Tok, Sheng Tony Hui, Wei‐Chun Tang, Arda Mizrak, Qingyue Zhang, Luke Cohen-Abeles, Robert V. Farese, Tobias C. Walther
The paper identifies adaptive pathways in hepatocytes that restore homeostasis during lipid overload by coordinating fatty acid oxidation and suppression of unsaturated fatty acid synthesis.
bioRxiv · Jul 7, 2026 · PreprintCell Biology