Author

Luke Cohen-Abeles

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Robert V. FareseiD· 2 shared Tobias C. WaltheriD· 2 shared Arda MizrakiD· 1 shared Do Hoon KwoniD· 1 shared Leehyeon KimiD· 1 shared Ozlem Tok· 1 shared Pei LiuiD· 1 shared Qingyue Zhang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Robert V. FareseORCID

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2 papers

Recent·Most cited

Cryo-EM structures reveal the mechanism of phosphatidylserine remodeling by membrane-bound glycerophospholipid O-acyltransferase 1

Leehyeon Kim, Siyoung Kim, Ritchie Ly, Luke Cohen-Abeles, Pei Liu, Xuejun Jiang, Do Hoon Kwon, Robert V. Farese, Tobias C. Walther

The paper determines how MBOAT1 remodels phosphatidylserine by solving its cryo-EM structures and combining them with lipidomics and simulations.

bioRxiv · Sep 3, 2026 · PreprintBiochemistry

A membrane homeostatic response to lipid overload coordinates fatty acid metabolism

Xiaojun Xiang, Yohannes Abere Ambaw, Ozlem Tok, Sheng Tony Hui, Wei‐Chun Tang, Arda Mizrak, Qingyue Zhang, Luke Cohen-Abeles, Robert V. Farese, Tobias C. Walther

The paper identifies adaptive pathways in hepatocytes that restore homeostasis during lipid overload by coordinating fatty acid oxidation and suppression of unsaturated fatty acid synthesis.

bioRxiv · Jul 7, 2026 · PreprintCell Biology