Author

P. A. Cote-Hammarlof

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:yeast· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Bank· 2 shared D. N. A. Bolon· 2 shared I. Fragata· 2 shared A. Rossouw· 1 shared C. Hollins· 1 shared D. Mavor· 1 shared J. Flynn· 1 shared J. M. Flynn· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersEvolutionary Biology

C. Bank

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2 papers

Recent·Most cited

The adaptive potential of the middle domain of yeast Hsp90

P. A. Cote-Hammarlof, I. Fragata, J. Flynn, K. B. Zeldovich, C. Bank, D. N. A. Bolon

The paper quantifies how adaptation costs vary across environments by analyzing mutations in the middle domain of yeast Hsp90, finding low adaptation cost and identifying regions enriched in beneficial or deleterious mutations.

bioRxiv · Jul 17, 2020Evolutionary Biology

Comprehensive fitness maps of Hsp90 show widespread environmental dependence

J. M. Flynn, A. Rossouw, P. A. Cote-Hammarlof, I. Fragata, D. Mavor, C. Hollins, C. Bank, D. N. A. Bolon

This study maps the fitness effects of Hsp90 variants across multiple environments, showing widespread environmental dependence and selection for robustness.

bioRxiv · Dec 9, 2019Evolutionary Biology