The cyclic dinucleotide 2'3'-cGAMP induces a broad anti-bacterial and anti-viral response in the sea anemone Nematostella vectensis
S. R. Margolis, P. A. Dietzen, B. M. Hayes, S. C. Wilson, B. C. Remick, S. Chou, R. E. Vance
This study shows that 23-cGAMP induces both anti-viral and anti-bacterial gene expression in the sea anemone Nematostella vectensis, suggesting an ancestral role for cyclic dinucleotide signaling in immunity.
bioRxiv · May 13, 2021Immunology