Author

B. M. Hayes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Organism:mouse· 2

Frequent Co-Authors

S. Chou· 4 shared Z. Zhao· 3 shared A. D. Radkov· 1 shared A. L. Sapiro· 1 shared A. Radkov· 1 shared B. C. Remick· 1 shared B. W. Zaro· 1 shared B.-M. Koo· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersMicrobiology

S. Chou

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4 papers

Recent·Most cited

Lipopolysaccharide integrity primes bacterial sensitivity to a cell wall-degrading intermicrobial toxin

K. L. Trotta, B. M. Hayes, J. P. Schneider, J. Wang, H. Todor, P. Rockefeller Grimes, Z. Zhao, W. Hatleberg, M. R. Silvis, R. Kim, B.-M. Koo, M. Basler, S. Chou

The paper identifies genes in Escherichia coli that affect susceptibility to a cell wall-degrading toxin from Pseudomonas aeruginosa, revealing the role of lipopolysaccharide in modulating toxin toxicity.

bioRxiv · Jan 20, 2023 · PreprintMicrobiology

Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission

A. L. Sapiro, B. M. Hayes, R. F. Volk, J. Y. Zhang, D. M. Brooks, C. Martyn, A. Radkov, Z. Zhao, M. Kinnersley, P. R. Secor, B. W. Zaro, S. Chou

This study maps transcriptome changes in Borrelia burgdorferi during tick-borne transmission by analyzing gene expression over four days in ticks.

bioRxiv · Nov 9, 2022 · PreprintMicrobiology

The cyclic dinucleotide 2'3'-cGAMP induces a broad anti-bacterial and anti-viral response in the sea anemone Nematostella vectensis

S. R. Margolis, P. A. Dietzen, B. M. Hayes, S. C. Wilson, B. C. Remick, S. Chou, R. E. Vance

This study shows that 23-cGAMP induces both anti-viral and anti-bacterial gene expression in the sea anemone Nematostella vectensis, suggesting an ancestral role for cyclic dinucleotide signaling in immunity.

bioRxiv · May 13, 2021Immunology

Immune factor of bacterial origin protects ticks against host microbial commensals

B. M. Hayes, A. D. Radkov, F. Yarza, S. Flores, J. R. Kim, Z. Zhao, K. W. Lexa, L. Marnin, J. Biboy, V. Bowcutt, W. Vollmer, J. H. Pedra, S. Chou

This study shows that a bacterial-derived immune factor in ticks protects them from host skin microbes but not from Lyme disease bacteria, revealing a complex interplay between ticks, their microbes, and hosts.

bioRxiv · Apr 10, 2020Evolutionary Biology