Author

P. A. Jansen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

B. Campo· 2 shared G. Trevitt· 2 shared J. M. Bolscher· 2 shared J. Schalkwijk· 2 shared K. J. Dechering· 2 shared K. M. Koolen· 2 shared L. E. de Vries· 2 shared M. Llinas· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

B. Campo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The moon's influence on the activity of tropical forest mammals

R. Bischof, A. F. Vallejo Vargas, A. Semper-Pascual, S. Schowanek, L. Beaudrot, D. Turek, P. A. Jansen, F. Rovero, S. E. Johnson, M. G. M. Lima, F. Santos, E. Uzabaho, S. Espinosa, J. A. Ahumada, R. Bitariho, , D. Sheil

The paper examines how tropical forest mammals respond to lunar cycles using camera trapping data, finding that 16% avoid moonlight while 3% are attracted to it.

bioRxiv · Feb 20, 2024Ecology

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

L. E. de Vries, P. A. Jansen, C. Barcelo, J. Munro, J. M. Verhoef, C. F. A. Pasaje, K. Rubiano, J. Striepen, J. M. Bolscher, R. Henderson, T. Huijs, K. M. Koolen, P. K. Tumwebaze, T. Yeo, A. C. Aguiar, , K. J. Dechering

This paper characterizes MMV693183, a novel antimalarial compound targeting acetyl-CoA synthetase, showing in vitro and in vivo efficacy against Plasmodium species and transmission blocking.

bioRxiv · May 12, 2021Microbiology

Antimalarial pantothenamide metabolites target acetyl-CoA synthesis in Plasmodium falciparum

J. Schalkwijk, E. L. Allman, P. A. Jansen, L. E. de Vries, S. Jackowski, P. N. Botman, C. A. Beuckens-Schortinghuis, K. M. Koolen, J. M. Bolscher, M. W. Vos, K. Miller, S. Reeves, H. Pett, G. Trevitt, S. Wittlin, , K. J. Dechering

Pantothenamides form antimetabolites that interfere with acetyl-CoA metabolism in the human malaria parasite Plasmodium falciparum.

bioRxiv · Feb 12, 2018Pharmacology & Toxicology