Author

P. A. McLaughlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. W. M. Van der Velden· 1 shared C. Liu· 1 shared H. V. Han· 1 shared K. Pham· 1 shared L. M. Ballou· 1 shared N. Sivaram· 1 shared O. Petrenko· 1 shared R. Z. Lin· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. W. M. Van der Velden

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1 paper

Recent·Most cited

PIK3CA in KrasG12D/Trp53R172H Tumor Cells Promotes Immune Evasion by Limiting Infiltration of T Cells in a Model of Pancreatic Cancer

N. Sivaram, P. A. McLaughlin, H. V. Han, O. Petrenko, Y.-P. Jiang, L. M. Ballou, K. Pham, C. Liu, A. W. M. Van der Velden, R. Z. Lin

This study shows that PIK3CA-AKT signaling in pancreatic cancer cells limits T cell infiltration and tumor clearance by reducing MHC Class I and CD80 expression, suggesting it as a target for immunotherapy.

bioRxiv · Jan 15, 2019 · PreprintCancer Biology