Author

P. D. Vogel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

J. G. Wise· 2 shared J. W. McCormick· 2 shared C. A. Follit· 1 shared C. Park· 1 shared G. Chen· 1 shared L. A. McCormick· 1 shared L. Ammerman· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

J. G. Wise

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2 papers

Recent·Most cited

Computationally accelerated identification of P-glycoprotein inhibitors

L. A. McCormick, J. W. McCormick, C. Park, C. A. Follit, J. G. Wise, P. D. Vogel

This study identifies nine novel P-gp inhibitors using a computationally accelerated drug discovery pipeline, showing they reverse multidrug resistance in cancer cells with minimal toxicity to non-cancerous cells.

bioRxiv · Mar 5, 2024 · PreprintCancer Biology

Transport of Alzheimer's Associated Amyloid-β Catalyzed by P-glycoprotein

J. W. McCormick, L. Ammerman, G. Chen, P. D. Vogel, J. G. Wise

This study shows P-glycoprotein actively transports amyloid-β proteins, suggesting a role in Alzheimer's disease progression.

bioRxiv · Oct 22, 2020Biochemistry