P. F. Huesgen

Bioengineering secreted proteases converts divergent Rcr3 orthologs and paralogs into extracellular immune co-receptors

This study bioengineers proteases to convert Rcr3 orthologs and Pip1 into immune co-receptors that trigger Avr2/Cf-2 dependent immunity in tomato.

Repression of pattern-triggered immune responses by hypoxia in Arabidopsis

This study shows hypoxia represses key aspects of plant immunity by interfering with transcriptional programs and immune signaling pathways.

Phytocystatin 6 is a context-dependent, tight-binding inhibitor of Arabidopsis thaliana legumain isoform β

The paper identifies AtCYT6 as a tight-binding inhibitor of AtLEGβ in Arabidopsis, revealing its dual inhibition mechanism and context-dependent regulation.

Combination of transcriptomic, proteomic and degradomic profiling reveals common and distinct patterns of pathogen-induced cell death in maize

A bipartite chromatophore transit peptide and N-terminal processing of protein in the Paulinella chromatophore

The study identifies a bipartite N-terminal targeting sequence in proteins imported into the Paulinella chromatophore, with only the N-terminal third being cleaved during import.

Epichloe festucae in mutualistic association with Lolium perenne suppresses host apoplastic cysteine protease activity

This study identifies and characterizes apoplastic cysteine proteases in Lolium perenne and shows that mutualistic Epichloe festucae suppresses their activity through potential inhibitors like LpCys1.

Sensitive determination of proteolytic proteoforms in limited microscale proteome samples

The paper introduces a method for identifying thousands of N-termini from small samples, demonstrating its application across various biological contexts.