Author

W. T. Soh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Ono· 2 shared E. E. Nakayama· 2 shared H. Arase· 2 shared H. Nakagami· 2 shared S. Torii· 2 shared T. Shioda· 2 shared Y. Liu· 2 shared Y. Matsuura· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Ono

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Phytocystatin 6 is a context-dependent, tight-binding inhibitor of Arabidopsis thaliana legumain isoform β

N. P. Santos, W. T. Soh, F. Demir, R. Tenhaken, P. Briza, P. F. Huesgen, H. Brandstetter, E. Dall

The paper identifies AtCYT6 as a tight-binding inhibitor of AtLEGβ in Arabidopsis, revealing its dual inhibition mechanism and context-dependent regulation.

bioRxiv · May 22, 2023 · PreprintBiochemistry

An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies

Y. Liu, W. T. Soh, A. Tada, A. Arakawa, S. Matsuoka, E. E. Nakayama, S. Li, C. Ono, S. Torii, K. Kishida, H. Jin, W. Nakai, N. Arase, A. Nakagawa, Y. Shindo, , H. Arase

This study identifies an NTD site on SARS-CoV-2 spike protein that enhances infectivity when targeted by antibodies, and finds these antibodies are present in hospitalized patients and some uninfected donors.

bioRxiv · Dec 18, 2020Microbiology

The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN

W. T. Soh, Y. Liu, E. E. Nakayama, C. Ono, S. Torii, H. Nakagami, Y. Matsuura, T. Shioda, H. Arase

This study identifies L-SIGN and DC-SIGN as receptors for the N-terminal domain of SARS-CoV-2 spike protein, showing their role in infection and the importance of anti-NTD antibodies.

bioRxiv · Nov 5, 2020 · PreprintMicrobiology

In silico design of Phl p 6 variants with altered folding stability significantly impacts antigen processing, immunogenicity and immune polarization

P. Winter, S. Stubenvoll, S. Scheiblhofer, I. A. Joubert, L. Strasser, C. Briganser, W. T. Soh, F. Hofer, A. S. Kamenik, V. Dietrich, S. Michelini, J. Laimer, P. Lackner, J. Horejs-Hoeck, M. Tollinger, , R. Weiss

bioRxiv · Feb 26, 2020Immunology